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The Sugarland duo, Jennifer Nettles and Kristian Bush, will join rock star Melissa Etheridge for the big final number. Plus, Carrie Underwood and LeAnn Rimes will team with several female stars for a new song, “Just Stand Up,” which will premiere on the special.
Other top celebrities confirmed to participate in the show are Jennifer Aniston, Halle Berry, Jessica Alba, Katie Couric, Sally Field, Meryl Streep and many others. The event is intended to bring attention to the fight against cancer.